fatigued; weary; exhausted. in a state of poor health: He was in a run-down condition from months of overwork. in neglected condition; fallen into disrepair: a run-down house.

What does it mean when a person is run down?

: in very bad condition because of age or lack of care. : in poor health or physical condition : worn-out or exhausted.

What does rundown mean in business?

ECONOMICS. the process of making a business or industry smaller or of ending its operations completely: the rundown of sth The region has been battered by the rundown of the coal and steel industries.