In mild forms of TTP or HUS the physician may falsely attribute the anemia to intermittent bleeding secondary to the low platelet counts from ITP. A large number of schistocytes associated with the hemolytic process should be seen in the former disease processes.

What is the difference between idiopathic and immune thrombocytopenic purpura?

Idiopathic thrombocytopenic purpura is an immune disorder in which the blood doesn't clot normally. This condition is now more commonly referred to as immune thrombocytopenia (ITP). ITP can cause excessive bruising and bleeding.

What conditions cause schistocytes?

Conditions. Schistocytes on the peripheral blood smear is a characteristic feature of microangiopathic hemolytic anemia(MAHA). The causes of MAHA can be disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome, HELLP syndrome, malfunctioning cardiac valves etc.