The primary function of fixatives is to prevent autolysis (enzymes attack) as well as putrefaction (bacterial attack) of tissues.

What is a fixative and why is it used?

A fixative is a stabilizing or preservative agent: Dye fixatives or mordants, are chemical substances used in processing fabrics to create circumstances in the micro-substrates causing dye molecules to adhere and remain that way.

What is the importance of fixatives in tissue processing?

The importance of fixation

The broad objective of tissue fixation is to preserve cells and tissue components in a “life-like state” and to do this in such a way as to allow for the preparation of thin, stained sections.