The Intel Serial IO driver is required if you plan to use the I2C, UART, or GPIO host controllers. Not sure if this is the right driver for your Intel NUC? Run Intel® Driver & Support Assistant to automatically detect driver updates.

Is Intel Serial IO important?

The IO driver is responsible for interconnect capability betwen the host controller and various hardware and the operating system. It is a separate but required component companion to the Intel chipset inf package for many systems.

What is serial IO?

serial input/output (SIO) A method of communicating data between devices, typically a computer and its peripherals, the individual data bits being sent sequentially. ... Asynchronous methods are generally used with dial-up modems or for general connection of simple serial peripherals.