Traditionally, enquire simply meant “ask,” while inquire was used for formal investigations. In the UK, the two words are used interchangeably, although inquire is still the more commonly used word for formal or official investigations. In the United States, inquire is the strongly preferred spelling in all uses.

How do you use inquire?

1 : to ask or ask about I inquired about the schedule. 2 : to make an investigation The committee inquired into the matter. 3 : to ask a question "Can I help you?" she inquired.

Do you make an inquiry or enquiry?

There is a very simple answer here - there is no difference in meaning. The spelling with 'e' is British, the spelling with 'i' is North American. The same goes for the nouns, 'inquiry' and 'enquiry'. There are of course other differences in spelling between American and British English.