When the tubulin concentration is diluted below the Cc, the microtubules disassemble twice as rapidly at the (+) end as at the (−) end. Thus both assembly and disassembly occur preferentially at the (+) end (Figure 19-10b).
What phase do microtubules disassemble?
During prophase of mitosis, the duplicated centrosomes separate and move to opposite sides of the nucleus. The nuclear envelope then disassembles, and microtubules (more...)
Why do microtubules disassemble in mitosis?
During prophase, when levels of mitotic kinase activity rise, interphase microtubules were gradually disassembled, in part as a result of phosphorylation-induced inactivation of the microtubule stabiliser Ensconsin/MAP7.
