Denosumab injection comes as a solution (liquid) to be injected subcutaneously (under the skin) in your upper arm, upper thigh, or stomach area. It is usually injected by a doctor or nurse in a medical office or clinic. Denosumab injection (Prolia) is usually given once every 6 months.

Is Prolia an injection or infusion?

Prolia is given by healthcare providers as an injection under your skin (called a subcutaneous injection). You'll get Prolia injections in your doctor's office once every 6 months. Reclast is given as an intravenous (IV) infusion. With an IV infusion, the drug is injected into your vein over a period of time.

Does Prolia come with needle?

Prolia is supplied in a single-dose prefilled syringe with a safety guard. The gray needle cap on the single-dose prefilled syringe contains dry natural rubber (a derivative of latex).