You can use slice! You just have to make sure you know how to use it. Positive #s are relative to the beginning, negative numbers are relative to the end.

js>"12345.00".slice(0,-1)
12345.0

You can use the substring method of JavaScript string objects:

s = s.substring(0, s.length - 4)

It unconditionally removes the last four characters from string s.

However, if you want to conditionally remove the last four characters, only if they are exactly _bar:

var re = /_bar$/;
s.replace(re, "");

The easiest method is to use the slice method of the string, which allows negative positions (corresponding to offsets from the end of the string):

const s = "your string";
const withoutLastFourChars = s.slice(0, -4);

If you needed something more general to remove everything after (and including) the last underscore, you could do the following (so long as s is guaranteed to contain at least one underscore):

const s = "your_string";
const withoutLastChunk = s.slice(0, s.lastIndexOf("_"));
console.log(withoutLastChunk);

For a number like your example, I would recommend doing this over substring:

console.log(parseFloat('12345.00').toFixed(1));

Do note that this will actually round the number, though, which I would imagine is desired but maybe not:

console.log(parseFloat('12345.46').toFixed(1));

Using JavaScript's slice function:

let string = 'foo_bar';
string = string.slice(0, -4); // Slice off last four characters here
console.log(string);

This could be used to remove '_bar' at end of a string, of any length.

Be aware that String.prototype.{ split, slice, substr, substring } operate on UTF-16 encoded strings

None of the previous answers are Unicode-aware. Strings are encoded as UTF-16 in most modern JavaScript engines, but higher Unicode code points require surrogate pairs, so older, pre-existing string methods operate on UTF-16 code units, not Unicode code points. See: Do NOT use .split('').

const string = "ẞ🦊";

console.log(string.slice(0, -1)); // "ẞ\ud83e"
console.log(string.substr(0, string.length - 1)); // "ẞ\ud83e"
console.log(string.substring(0, string.length - 1)); // "ẞ\ud83e"
console.log(string.replace(/.$/, "")); // "ẞ\ud83e"
console.log(string.match(/(.*).$/)[1]); // "ẞ\ud83e"

const utf16Chars = string.split("");

utf16Chars.pop();
console.log(utf16Chars.join("")); // "ẞ\ud83e"

In addition, RegExp methods, as suggested in older answers, don’t match line breaks at the end:

const string = "Hello, world!\n";

console.log(string.replace(/.$/, "").endsWith("\n")); // true
console.log(string.match(/(.*).$/) === null); // true