The gender of Kang and Kodos has been questioned numerous times, with Kodos often referred to as Kang's sister, though they have also been referred to as male on occasion. However, in the Season 26 special "Simpsorama" that sees "The Simpsons" meet the cast of "Futurama," a significant reveal implies a new layer to the duo's relationship. At the end of the episode, Kang and Kudos land on the "Futurama" planet Omicron Persei 8 to have dinner with Emperor Lrr (voiced by Maurice LaMarche) and his queen Ndnd (Tress MacNeille). When the two, whose last names are Johnson, land on the planet, Lrr asks for the female member of the duo to comfort his distraught wife. Both Kang and Kodos follow Ndnd, meaning both identify as female. 

"Simpsons" executive producer Al Jean would explain further to Entertainment Weekly. "We've implied androgyny, we've implied that one might be a woman — we never said that both were, but why not? Who knows?" he says. "People are asking: is this episode canon? ... Yeah, sure, they're Kang and Kodos Johnson. They're a gay female couple in their species. They seemed to be married." Whether "Simpsorama" is canon or not, it's gratifying to know that the show's creators are embracing such fluid ideas of identity and orientation for their characters.