Melissa is one of the celebrities who have been active in defending her personal profile low. It is believed that she is still single and has not been married yet.

Melissa made her acting debut in 1991. During that year, she has appeared in several television commercials for Rooms To Go and Ford. She made her television series debut in 1993 and that was in the TV series, Matlock. She made her first feature film debut in the 1995 movie, Mutant Species. Her breakthrough role came in 2010 after she played the role of Carol Peletier in the TV series, The Walking Dead. Her net worth is said to be around $3 million.