He is most well known for being the lead singer for the AOR bands Sorcery (1980-1983), Giuffria (1983–1988), Dirty White Boy (1988–1991), and Stream (1998). His biggest success came with the band Giuffria, when their hit single "Call to the Heart" reached #15 on the Billboard Hot 100 in early 1985. Eisley has also appeared in the television shows Beverly Hills, 90210 and 7th Heaven, the movie Action Jackson and has acted in various commercials. Eisley's rock ballad "Sweet Victory" was featured in the 2001 SpongeBob SquarePants episode "Band Geeks".