In 1960, along with Alan Arkin and others, Sand was a cast member of The Second City improvisational comedy troupe in Chicago. In 1966 he co-starred with Linda Lavin and Jo Ann Worley in the off-Broadway hit production The Mad Show, inspired by Mad Magazine. Sand's film credits include The Hot Rock, The Second Coming of Suzanne (in which he had a sex scene with Sondra Locke), and The Main Event.