Wyner was introduced to Producer Steven Bochco while appearing in Bochco's short-lived 1976 series, Delvecchio. This led to the role as Irwin Bernstein in Hill Street, and to roles in 4 subsequent Bochco productions: Doogie Howser, M.D., Brooklyn South, NYPD Blue and L.A. Law. Additionally, Wyner has appeared on the following programs for Hill Street's production company, MTM: Rhoda, The Bob Newhart Show, The White Shadow, WKRP in Cincinnati and Newhart.