So, what exactly is a pyrazine? Short for alkyl-methoxypyrazines, pyrazines are chemical compounds generally found in higher levels in the classic Bordeaux varietals- Sauvignon Blanc, Cabernet Franc, Cabernet Sauvignon, Merlot, Carménère and Malbec.

How is pyrazine made?

Many methods exist for the organic synthesis of pyrazine and its derivatives. Some of these are among the oldest synthesis reactions still in use. In the Staedel–Rugheimer pyrazine synthesis (1876) 2-chloroacetophenone is reacted with ammonia to the amino ketone, then condensed and then oxidized to a pyrazine.

What was pyrazine used for?

Methoxylated pyrazines are mainly used in the perfume industry to improve the odor of cosmetics and toiletries (fresh, green, woody, ambery, oriental, musky, minty, and herbaceous). Pyrazine flavors are often added to microwave foods because roasting odors are not formed in microwaves at temperatures below 200 °C.