In a chemical synapse, the postsynaptic membrane is the membrane that receives a signal (binds neurotransmitter) from the presynaptic cell and responds via depolarisation or hyperpolarisation. The postsynaptic membrane is separated from the presynaptic membrane by the synaptic cleft.

What is located on postsynaptic membrane?

The postsynaptic membrane contains specific ACh receptors (AChR), concentrated opposite the active zones. ... The α subunits each contain a binding site for ACh on the extracellular domain of the molecule. It is the two α subunits of the AChR that contain the ACh binding sites.

Which neuron is postsynaptic?

The neuron transmitting the signal is called the presynaptic neuron, and the neuron receiving the signal is called the postsynaptic neuron. Note that these designations are relative to a particular synapse—most neurons are both presynaptic and postsynaptic.