Since neither Trifexis nor Sentinel stop ticks, you will need to add one of the following to your monthly heartworm preventive one month before tick season begins and continuing until tick season ends.
Does Sentinel for dogs help with ticks?
So use Sentinel primarily to control worms, and Simparica for for fleas and ticks.
What tick prevention can be used with Sentinel?
Parastar Plus, (a topical) can be used in conjunction with Sentinel as needed or if needed for those pets who are exposed to ticks or need prevention of ticks. Advantage II (a topical) can be used in conjunction with Sentinel or just as needed with pets in populations or exposed to populations with high flea counts.