Healing from a sprain or wound can cause itchiness, especially if you have to wear some sort of cast, wrap, bandage, or compression tape. Itchiness can also happen as a result of the skin stretching when the area is swollen. It's also possible that the pain-relieving medications can cause you to itch as well.

Why do sprains itch when healing?

Experts say histamine, which the body releases as a wound heals, and high bilirubin levels, which can also increase as wounds heal, can cause itching.

Can muscle strain cause itching?

And since the nerve signals that communicate pain can sometimes be closely linked with the nerve signals for itch, itching muscles could also be a way that your body is processing stress from working out. So next time you workout and your muscle fibers start to itch, that's probably a good sign.