In physical organic chemistry, a kinetic isotope effect is the change in the reaction rate of a chemical reaction when one of the atoms in the reactants is replaced by one of its isotopes.

What is meant by isotopic effect?

: the variation of certain characteristics (as density and spectrum) of an element in accordance with the mass of the isotopes involved.

What is isotopic effect with example?

An intermolecular isotope effect refers to two equivalent dissociation pathways from two differently labeled molecules. As an example: C 2 H 5 Cl + • → C 2 H 4 + • + HCl C 2 D 5 Cl + • → C 2 D 4 + • + DCl.