Sarin is a nerve agent, which means it interferes with the normal signaling between nerve cells. It acts in much the same way as organophosphate insecticides, block nerve endings from allowing muscles to stop contracting. Death may occur when the muscles controlling breathing become ineffective, causing asphyxiation.

How does sarin affect the body?

Exposure to high doses of sarin can result in tremors, seizures, and hypothermia. A more severe effect of sarin is the build-up of ACh in the central nervous system (CNS) which causes paralysis and ultimately peripherally-mediated respiratory arrest, leading to death.

How does sarin kill?

Death will usually occur as a result of asphyxia due to the inability to control the muscles involved in breathing. Initial symptoms following exposure to sarin are a runny nose, tightness in the chest, and constriction of the pupils. ... Death may follow in one to ten minutes after direct inhalation.