Provera does not cause miscarriage, but some studies have shown that there may be a link between certain birth defects in mothers who are exposed to progestins such as Provera during the first trimester of pregnancy.

What happens if a pregnant woman takes Provera?

There may be an increased risk of minor birth defects in children whose mothers take this drug during the first 4 months of pregnancy. If you take Provera and later find out you were pregnant when you took it, be sure to discuss this with your doctor as soon as possible.

Does Provera protect against pregnancy?

It contains a type of progesterone hormone Depo-Provera® shots provide protection against pregnancy for up to 14 weeks — though you typically need to receive one shot every 12 weeks.