To defy, challenge, or frustrate one. Don't cross that guy if you want a job in publishing—he's a celebrated editor. Stephen has crossed me up so many times I just can't trust him anymore.

What does Dont be cross mean?

angry and annoyed; ill-humored; snappish: Don't be cross with me.

What you mean by cross?

1a : a structure consisting of an upright with a transverse beam used especially by the ancient Romans for execution. b often capitalized : the cross on which Jesus was crucified. 2a : crucifixion. b : an affliction that tries one's virtue, steadfastness, or patience We all have our crosses to bear.