In density gradient centrifugation the process is similar. ... The spinning from the centrifuge causes more dense particles to move to the outside edge. These particles have more mass and are carried further by their inertia. Less dense particles then settle towards the center of the sample.

What is the principle of density gradient centrifugation?

Density gradient centrifugation is reported as a tool for separation of bacteria from food matrices. The underlying principle is based on a decreasing density of the suspending solution and migration of the targets to the equilibrate portion of the sample tube during centrifugation.

What is density gradient centrifuge?

Fig. 1.3. Density gradient centrifugation, in its original and simplest form, is a mixture of particles layered over a medium whose density increases from top to bottom (A). In a short or slow centrifugation large particles sediment more rapidly than small particles (B).