Hippos coexist with a variety of large predators. Nile crocodiles

, lions and spotted hyenas are known to prey on young hippos. However, due to their aggression and size, adult hippos are not usually preyed upon by other animals.

Does the Hippopotamus have any predators?

In the unpredictable African wilderness, hippos face many perils, such as disease and drought. A full-grown adult doesn't have much in the way of natural predators. ... Crocodiles, lions, hyenas, and leopards are all potential threats while growing up—but the most dangerous thing to a young hippo is another hippo.

What animal can kill a hippo?

Besides lions, the Spotted Hyena and the Nile crocodile are the other predators for hippopotamuses. Due to the size and aggression, adult hippos are rarely preyed on and the predators only target the young calves. A hippo fighting (and defeating) a massive Nile crocodile.