Hyperpolarization is a phase where some potassium channels remain open and sodium channels reset. A period of increased potassium permeability results in excessive potassium efflux before the potassium channels close. This results in hyperpolarization as seen in a slight dip following the spike.

Which channels are open during hyperpolarization?

On hyperpolarization, HCN channels open and carry a Na⁺ inward current that in turn depolarizes the cell. They are modulated by cyclic nucleotides, and thereby, couple second-messenger signaling to electric activity (4). HCN channels, also known as pacemaker channels, serve diverse functions.

What happens during hyperpolarization quizlet?

Why does hyperpolarization occur? Potassium ions continue to diffuse out of the cell after the inactivation gates of the voltage-gated sodium ion channels begin to close. The extra efflux of potassium ions causes the membrane potential to become slightly more positive than the resting value.