A pituitary gland tumor is almost always the cause of gigantism. The pea-sized pituitary gland is located at the base of your brain. It makes hormones that control many functions in your body.

Who is most likely to get gigantism?

Gigantism is an extremely rare condition that only occurs in children. About 100 cases have been reported in the United States. Gigantism has been reported to occur at a female-to-male ratio of 1:2.

How common is gigantism?

Gigantism is extremely rare, with approximately 100 reported cases to date. Although still rare, acromegaly is more common than gigantism, with a prevalence of 36-69 cases per million and an incidence of 3-4 cases per million per year. Gigantism may begin at any age before epiphyseal fusion.