Sisko hates Picard in the DS9 premiere emissary. Sisko blames Picard for the death of his wife at the battle of Wolf 359. Although by the end of the episode Sisko is less hostile to Picard and it may be said that Sisko was simply caught up in his grief at this point.

Did Picard and Sisko meet?

This also retconned TOS so that canonically, Sisko and crew were in the episode all along. ... Ironically, Sisko met also Picard in DS9's premiere episode, "Emissary," and he had a hostile rapport with the Captain of the Enterprise-D.

What happens to Sisco at end of DS9?

He left DS9 at the end of the Dominion War to join the Bajoran Prophets, but returned to linear existence just in time for the birth of his daughter, Rebecca Jae Sisko. ... His wife Kasidy Yates and his daughter Rebecca joined him aboard the vessel, including during an extended exploration mission in the Gamma Quadrant.