Glimepiride is a derivative of a sulfonamide drug. People allergic to other sulfonamide-related drugs may develop an allergic reaction to glimepiride. Anyone who has an allergic reaction to sulfa drugs should not take glimepiride.

Does Amaryl have sulfa?

Not all drugs that contain sulfonamides cause reactions in all people. Many people with sulfa allergies and sensitivities may be able to safely take the following medications but should do so with caution: some diabetes medications, including glyburide (Glynase, Diabeta) and glimepiride (Amaryl)

Can you take glimepiride If you have a sulfa allergy?

Yep, you can take these. Glimepiride, glipizide, and glyburide are non-insulin medications that treat diabetes type 2. Yep, these are safe if you have a sulfa allergy.