In the revival series, season 5, set many years after the original conclusion of The Final Break, and after a very dramatic and drawn out death, we discover that Michael Scofield is very much alive.

Does Michael Scofield die in Season 4?

During the four year time jump at the end, it's revealed that Michael has died, with Sara, Lincoln, Sucre, Mahone, and Michael Scofield Jr. ... While it's assumed Michael died from the return of his brain tumor, the real explanation for his death is seen in Prison Break: The Final Break.

What kills Michael Scofield?

Although Scofield didn't technically die on screen, that still seems like a pretty unquestionable death. Not only was he dying from a brain tumor, but he electrocuted himself - leaving him dead twice over, with a memorial stone in place and a touching farewell message left for his loved ones.