Osteoblasts form a closely packed sheet on the surface of the bone, from which cellular processes extend through the developing bone. They arise from the differentiation of osteogenic cells in the periosteum, the tissue that covers the outer surface of the bone, and in the endosteum of the marrow cavity.

Where are osteoblasts produced?

OSTEOBLASTS are the cells that form new bone. They also come from the bone marrow and are related to structural cells. They have only one nucleus. Osteoblasts work in teams to build bone.

How are osteoblasts produced?

These bone-forming cells are formed when osteogenic cells differentiate in a tissue covering the outer surface of bone, called the periosteum. They also arise from osteogenic cell differentiation occurring in the endosteum, a structure found in the middle of bone and in the bone marrow.