Conclusion: Although kratom use has been associated with death and cardiotoxicity, especially at higher doses and when associated with other psychoactive drugs, the dearth of data and methodological limitations reported in existing studies do not allow a definitive conclusion, and further studies are still necessary to ...

Can kratom cause heart failure?

Other serious kratom side effects include: Cardiac issues, such as heart attack, abnormal heart rhythms and high blood pressure. Encephalopathy (brain disease).

Does kratom prolong QT?

Nevertheless, there were no differences in the odds of having prolonged QTc intervals between kratom users and controls. The estimated average daily intake of mitragynine consumed by kratom users was 434.28 mg.