Based on the current guidelines, an acute exacerbation is defined as an acute and transient worsening of preexisting symptoms in patients with CRS [7, 8].

Does exacerbation mean acute on chronic?

An acute exacerbation of chronic obstructive pulmonary disease or acute exacerbations of chronic bronchitis (AECB), is a sudden worsening of chronic obstructive pulmonary disease (COPD) symptoms including shortness of breath, quantity and color of phlegm that typically lasts for several days.

What's acute exacerbation mean?

Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) describe the phenomenon of sudden worsening in airway function and respiratory symptoms in patients with COPD. These exacerbations can range from self-limited diseases to episodes of florid respiratory failure requiring mechanical ventilation.