Method: The accurately weighed sample is added to the 5 ml of HCl and 50 ml of distilled water. Then the solution is cooled to 15 °C. Then the solution is slowly titrated with the 0.1 N sodium nitrite solution using starch iodide paper as the indicator. Used in the determination of the dopamine.
What is the method of diazotization titration?
Diazotization Titration or Nitrite Titration: Diazotization is used in the analysis of aromatic compounds containing an amino group in the molecules. This analysis is based on the reaction between aromatic primary amine (–NH2), HONO, in presence of excess mineral or inorganic acids.
Which type of drugs can be titrated diazotization titration?
Diazotization Titration are used to determination of primary aromatic amine compound.