No — not anymore. Offensive and defensive pass interference calls and non-calls were subject to the NFL's
Can you challenge a penalty call in the NFL?
Coaches get two challenges a game. If the coach fails the challenge, he's assessed a timeout. ... Coaches also can't challenge some judgment calls made by officials (holding, for example). A team can't commit a penalty before the next snap and then challenge.
Can NFL coaches challenge pass interference 2020?
After its introduction in 2019, the NFL's pass interference replay system will not return in 2020. ... Shortly after the announcement, Competition Committee chairman Rich McKay told SiriusXM NFL Radio that no one cared to bring it to a vote since the rule received little support.