You should apply a compression bandage as soon as a sprain occurs. Wrap your ankle with an elastic bandage, such as an ACE bandage, and leave it on for 48 to 72 hours.

How long should you keep a compression bandage on?

A compression bandage generally should be used for only 24 to 48 hours after an injury.

Should you keep a sprained ankle compressed?

Proper initial care of your sprained ankle is critical. A compression wrap helps decrease swelling. If swelling is kept to a minimum, it may help your ankle feel better. Applying a compression wrap is easy and can be done at home.