Pyonephrosis is a surgical emergency and needs immediate intervention. Pyonephrosis may be treated with either an antegrade or a retrograde decompression. Retrograde decompression, or placement of a ureteral stent, is indicated in stable patients with no signs of hemodynamic instability.

Is pyonephrosis curable?

Treating pyelonephritis

Although drugs can cure the infection within 2 to 3 days, the medication must be taken for the entire prescription period (usually 10 to 14 days). This is true even if you feel better. The antibiotic options are: levofloxacin.

What is the best treatment for pyelonephritis?

Outpatient oral antibiotic therapy with a fluoroquinolone is successful in most patients with mild uncomplicated pyelonephritis. Other effective alternatives include extended-spectrum penicillins, amoxicillin-clavulanate potassium, cephalosporins, and trimethoprim-sulfamethoxazole.