In the Lamarckian genetic algorithm, genotypic mutation plays a somewhat different role than it does in traditional genetic algorithms. Tradition- ally, mutation plays the role of a local search operator, allowing small, refining moves that are not efficiently made by crossover and selection alone.

What is meant by genetic algorithm?

A genetic algorithm (GA) is a method for solving both constrained and unconstrained optimization problems based on a natural selection process that mimics biological evolution.

What is genetic algorithm in docking?

A genetic algorithm (GA) for protein-protein docking is described, in which the proteins are represented by dot surfaces calculated using the Connolly program. The GA is used to move the surface of one protein relative to the other to locate the area of greatest surface complementarity between the two.