Unless you are starving for disk space and/or disk performance isnt an issue for data on this drive, then there is no need to enable file and folder compression off the bat.
Is it good to enable file and folder compression?
Compression should not be done on system drives and other program files. The computer accesses these modules quite frequently and compressing them will make things slower. Files already in a compressed format will not display any significant progress since they are already compressed.
Should I enable file and folder compression NTFS?
NTFS compression is ideal for: Files you rarely access. (If you never access the files, the potential slow-down when accessing them is unnoticeable.) Files in uncompressed format.