The lead researcher, Christopher Cascio said, “Many studies have shown that these circuits can do things like dampen pain and help us maintain balance in the face of threats.” Thus practising self-affirmation does help in activating those areas of the brain that makes you happy and positive.

Are affirmations scientifically proven?

The researchers found that affirmations focused on your existing values can lead to increased acceptance of positive health information and change in healthy behaviors: ... Having someone clearly state their values is helpful by giving them a sense of direction, in addition to increasing motivation for change.

What science says about affirmations?

It fires up your neural pathways and makes changes to those areas of the brain that makes you happy and positive. Various studies also confirm affirmations: decrease health-deteriorating stress, increase the amount of exercise people do, help you to eat more fruit and vegetables and achieve more academically.