A BCR-ABL genetic test looks for a genetic mutation (change) on a specific chromosome. Chromosomes are the parts of your cells that contain your genes. Genes are parts of DNA passed down from your mother and father. They carry information that determines your unique traits, such as height and eye color.
What does BCR-ABL negative mean?
Introduction. BCR/ABL negative or atypical chronic myeloid leukemia (CML) is a rare hematologic malignancy with an estimated incidence of 1–2% of BCR/ABL positive CML.
What is the normal value of BCR-ABL?
The effective measurement range for the international scale was deemed to be a BCR-ABL level of 10% IS or below. This was because most field methods used ABL as the control gene.