The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem that provides the far-reaching noradrenergic neurotransmitter system of the brain.

Is locus coeruleus in midbrain?

The locus coeruleus (\-si-ˈrü-lē-əs\) (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic.

What contains the locus coeruleus?

The nucleus locus coeruleus in the brain is located in the posterior area of the rostral pons in the lateral floor of the fourth ventricle. Neurons from this nucleus project axons to most, if not all, areas of the brain and into the spinal cord as denoted by the red arrows.