Non-selective or non-specific beta blockers
That means they block both beta1 and beta2 receptors and so affect the heart, lungs, vascular smooth muscles, kidneys, GI, etc.
What do nonselective beta-blockers do?
On average, nonselective beta-blockers lowered blood pressure by about 10 mmHg systolic and 7 mmHg diastolic, and reduced heart rate by 12 beats per minute.
How do beta-blockers differ from selective and nonselective?
There is a clear difference between beta 1-selective and nonselective beta-blockers on quality-of-life (QOL) perception. During treatment with nonselective beta-blockers, QOL perception is lower than during treatment with beta 1-selective drugs.