Protease is produced in the stomach, pancreas, and small intestine. Most of the chemical reactions occur in the stomach and small intestine. In the stomach, pepsin is the main digestive enzyme attacking proteins. Several other pancreatic enzymes go to work when protein molecules reach the small intestine.

Where is protease produced and released?

Proteases are released by the pancreas into the proximal small intestine, where they mix with proteins already denatured by gastric secretions and break them down into amino acids, the building blocks of protein, which will eventually be absorbed and used throughout the body.

What is the source of protease?

2.1 Sources of Proteases. Proteases from all sources, that is, bacteria, fungi, virus, plants, animals, and humans, have been identified because of their important physiological roles. On the basis of site of action on protein substrates, they are broadly classified as endo-peptidases or exo-peptidases.