Hemolysis is known to cause a variable interference in both cardiac troponin I (cTnI) and troponin T (cTnT) assays. Each laboratory should determine and publicize these effects.
What can falsely elevated troponin?
This may be observed in several well-known situations including pulmonary embolism, pericarditis, myocarditis, coronary vasospasm, sepsis, congestive heart failure, supraventricular tachycardia with hemodynamic compromise, re-nal insufficiency, and prolonged strenuous endurance exercise.
What can affect troponin levels?
Causes of high troponin levels
- sepsis, which is a severe and potentially life-threatening reaction to an infection entering the bloodstream.
- kidney failure or chronic kidney disease.
- heart failure.
- chemotherapy-related damage to the heart.
- pulmonary embolism.
- heart infection.
- myocarditis, which is inflammation of the heart.
