Splinters aren't deadly in and of themselves. Neither really are blisters, scratches, or other seemingly superficial assaults on our skin. But these nicks allow for something much deadlier to make entry into our otherwise sealed-off selves: Harmful bacteria like Staphylococcus aureus or Group A strep.

What happens to a splinter if not removed?

If the splinter isn't removed, the body probably won't absorb the invader or break it down. Rather, the body will likely try to push the splinter out, Biehler said. The splinter may cause an inflammatory reaction, which could mean swelling and redness in that area.

Can a splinter work itself out?

Tiny, pain-free slivers near the skin surface can be left in. They will slowly work their way out with normal shedding of the skin. Sometimes, the body also will reject them by forming a little pimple. This will drain on its own.