Which Functional Groups Are Acidic?

Which Functional Groups Are Acidic?

8.2.
Representative surface acidic functional groups are carbonyl, carboxyl, phenolic hydroxyl, and lactone groups.

Which functional groups are the most acidic?

The carboxylate is resonance stabilised to a very significant extent, as the negative charge on oxygen is delocalised extensively between 2 electronegative oxygens. This makes the carboxylate very stable, hence carboxylic acid is the most acidic functional group.

How do you know if a functional group is acidic or basic?

There are two key features of an acidic functional group: the presence of a hydrogen atom that can dissociate from the group (H+), and the ability of the remaining atoms to delocalize the resulting negative charge via resonance.

Maya Lin-Takahashi
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Maya Lin-Takahashi

Maya is a hardware enthusiast who tests and reviews smart home devices, smartphones, wearables, and audio gear. She focuses on practical consumer value and build quality.