DNA replication occurs in the cytoplasm of prokaryotes and in the nucleus of eukaryotes. Regardless of where DNA replication occurs, the basic process is the same. The structure of DNA lends itself easily to DNA replication.

Where does DNA replication take place?

As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).

Where does DNA replication occur in humans?

DNA replication happens in the nucleus of human cells. It will also take place within mitochondrial matrix.