Callie starts a new relationship with Penny Blake and leaves to go to New York with her in the season 12 finale. Shonda Rhimes spoke on Ramirez's abrupt departure, saying, "This one was different because it wasn't a big planned thing.

Why did Callie Torres leave GREY's anatomy?

Callie started dating Penny and wanted to move to New York with her, but after a custody battle with Arizona over their daughter, Sofia, she broke up with Penny. Arizona ended up offering her a custody agreement so she could move to New York, and so Callie left Grey's Anatomy in season 12.

What season does Torres leave GREY's?

After the season 12 Grey's Anatomy finale aired (which saw Callie reaching a joint custody agreement with her ex Arizona and moving to New York City), Sara Ramirez released a statement expressing their gratitude for their time with Grey's and explaining their decision to leave the show (via Entertainment Weekly).