Common causes of focal hyperpigmentation include injury, inflammation, phytophotodermatitis, lentigines, melasma, freckles, café-au-lait macules, and acanthosis nigricans. Common causes of widespread hyperpigmentation include melasma, drugs, cancers, and other systemic disorders.
What conditions can cause hyperpigmentation?
Some of the causes of hyperpigmentation include:
- Excess sun exposure.
- Certain chemotherapy drugs.
- Pregnancy.
- Certain medical conditions such as systemic lupus erythematosus (SLE)
- Allergies.
- Chemical or physical injury.
- Inflammatory diseases.
- Tobacco smoking.
Which lesion is Hyperpigmented?
The most frequent benign hyperpigmented skin lesions are melanocytic nevi, most commonly known as moles. These are benign proliferations of a type of melanocyte called nevus cells, which cluster as nests within the lower epidermis and dermis.