Inotropic: Affecting the force of muscle contraction. An inotropic heart drug is one that affects the force with which the heart muscle contracts. Ionotropic can be negative or positive.

What are examples of inotropes?

Inotropic agents such as milrinone, digoxin, dopamine, and dobutamine are used to increase the force of cardiac contractions.

What causes negative inotropic effect?

The negative inotropic effect is attributable to a potassium-induced reduction in the amplitude and/or duration of the action potential plateau.