Penicillin works against gram-positive bacteria, such as Staphylococcus and Pneumococcus by disrupting bacterial cell wall synthesis-- crosslinking of the peptidoglycan polymers is prevented by inhibition of the enzyme transpeptidaase, causing the malformed cells walls to take on excess water, which causes them to ...

How does penicillin work on bacteria?

Share on Pinterest Penicillins work by bursting the cell wall of bacteria. Drugs in the penicillin class work by indirectly bursting bacterial cell walls. They do this by acting directly on peptidoglycans, which play an essential structural role in bacterial cells.

What is the function of Penicillium?

1.1 Introduction. Penicillium is an important genus of phylum ascomycota, found in the natural environment as well as in food and drug production. Some members of the genus produce penicillin, a molecule used as an antibiotic that kills or stops the growth of certain kinds of bacteria inside the body.